CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Astacin |
Enzyme Information
| 3.4.24.21 |
Astacin.
based on mapping to UniProt P07584
Hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.
-!- A digestive endopeptidase from the cardia of the crayfish Astacus fluviatilis. -!- Belongs to peptidase family M12A. -!- Formerly EC 3.4.99.6.
|
UniProtKB Entries (1)
| P07584 |
ASTA_ASTAS
Astacus astacus
Astacin
|
PDB Structure
| PDB | 1IAD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Refined 1.8 A X-ray crystal structure of astacin, a zinc-endopeptidase from the crayfish Astacus astacus L. Structure determination, refinement, molecular structure and comparison with thermolysin.
J.Mol.Biol.
|
