CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.190 | Protein-Tyrosine Phosphatase; Chain A |
|
3.90.190.10 | Protein tyrosine phosphatase superfamily |
Domain Context
CATH Clusters
| Superfamily | Protein tyrosine phosphatase superfamily |
| Functional Family | mRNA-capping enzyme |
Enzyme Information
| 2.7.7.50 |
mRNA guanylyltransferase.
based on mapping to UniProt O55236
GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
-!- Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn.
|
| 3.1.3.33 |
Polynucleotide 5'-phosphatase.
based on mapping to UniProt O55236
A 5'-phosphopolynucleotide + H(2)O = a polynucleotide + phosphate.
-!- Does not act on nucleoside monophosphates. -!- Induced in Escherichia coli by T-even phages.
|
UniProtKB Entries (1)
| O55236 |
MCE1_MOUSE
Mus musculus
MRNA-capping enzyme
|
PDB Structure
| PDB | 1I9S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J.
|
