CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.600 | Farnesyl Diphosphate Synthase |
|
1.10.600.10 | Farnesyl Diphosphate Synthase |
Domain Context
CATH Clusters
| Superfamily | Farnesyl Diphosphate Synthase |
| Functional Family | Isoprene synthase, chloroplastic |
Enzyme Information
| 4.2.3.61 |
5-epiaristolochene synthase.
based on mapping to UniProt Q40577
(2E,6E)-farnesyl diphosphate = (+)-5-epiaristolochene + diphosphate.
-!- Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium.
|
UniProtKB Entries (1)
| Q40577 |
5EAS_TOBAC
Nicotiana tabacum
5-epi-aristolochene synthase
|
PDB Structure
| PDB | 1HX9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Single Active Site Mutations Change the Specificity of a Sesquiterpene Cyclase
To be Published
|