CATH Classification

Domain Context

CATH Clusters

Superfamily UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Functional Family UDP-N-acetylenolpyruvoylglucosamine reductase

Enzyme Information

1.3.1.98
UDP-N-acetylmuramate dehydrogenase.
based on mapping to UniProt P61431
UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

UniProtKB Entries (1)

P61431
MURB_STAAU
Staphylococcus aureus
UDP-N-acetylenolpyruvoylglucosamine reductase

PDB Structure

PDB 1HSK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A structural variation for MurB: X-ray crystal structure of Staphylococcus aureus UDP-N-acetylenolpyruvylglucosamine reductase (MurB).
Benson, T.E., Harris, M.S., Choi, G.H., Cialdella, J.I., Herberg, J.T., Martin Jr., J.P., Baldwin, E.T.
Biochemistry
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