CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.285 | Glutamate Dehydrogenase; Chain A, domain 3 |
|
1.10.285.10 | Glutamate Dehydrogenase, chain A, domain 3 |
Domain Context
CATH Clusters
| Superfamily | Glutamate Dehydrogenase, chain A, domain 3 |
| Functional Family | Glutamate dehydrogenase |
Enzyme Information
| 1.4.1.2 |
Glutamate dehydrogenase.
based on mapping to UniProt P24295
L-glutamate + H(2)O + NAD(+) = 2-oxoglutarate + NH(3) + NADH.
|
UniProtKB Entries (1)
| P24295 |
DHE2_CLOSY
[Clostridium] symbiosum
NAD-specific glutamate dehydrogenase
|
PDB Structure
| PDB | 1HRD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures.
Structure
|
