CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.40 | 3-Layer(aba) Sandwich |
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3.40.50 | Rossmann fold |
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3.40.50.960 | Lumazine/riboflavin synthase |
Domain Context
CATH Clusters
Superfamily | Lumazine/riboflavin synthase |
Functional Family | 6,7-dimethyl-8-ribityllumazine synthase |
Enzyme Information
2.5.1.78 |
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt O66529
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.
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UniProtKB Entries (1)
O66529 |
RISB_AQUAE
Aquifex aeolicus VF5
6,7-dimethyl-8-ribityllumazine synthase
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PDB Structure
PDB | 1HQK |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons.
J.Mol.Biol.
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