CATH Domain 1hfeL03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.950	Fe-only Hydrogenase (Larger Subunit); Chain L, domain 3
	3.40.950.10	Fe-only Hydrogenase (Larger Subunit); Chain L, domain 3

Domain Context

CATH Clusters

Superfamily	Fe-only Hydrogenase (Larger Subunit); Chain L, domain 3
Functional Family	NADP-reducing hydrogenase subunit HndD

Enzyme Information

1.12.7.2

Ferredoxin hydrogenase.

based on mapping to UniProt P07598

H(2) + 2 oxidized ferredoxin = 2 reduced ferredoxin + 2 H(+).

-!- Can use molecular hydrogen for the reduction of a variety of substances. -!- Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1 and EC 1.98.1.1.

UniProtKB Entries (1)

P07603

PHFS_DESVH

Desulfovibrio vulgaris str. Hildenborough

Periplasmic [Fe] hydrogenase small subunit

PDB Structure

PDB	1HFE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Desulfovibrio desulfuricans iron hydrogenase: the structure shows unusual coordination to an active site Fe binuclear center. Nicolet, Y., Piras, C., Legrand, P., Hatchikian, C.E., Fontecilla-Camps, J.C. Structure Fold.Des.