CATH Domain 1hb0B01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Chymotrypsin-like elastase family member 1

Enzyme Information

3.4.21.36

Pancreatic elastase.

based on mapping to UniProt P00772

Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.

-!- Formed by activation of proelastase from mammalian pancreas by trypsin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.7 and EC 3.4.21.11.

UniProtKB Entries (1)

P00772

CELA1_PIG

Sus scrofa

Chymotrypsin-like elastase family member 1

PDB Structure

PDB	1HB0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J. Nat.Struct.Biol.