1 keywords

CATH Domain 1h5sC00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.550 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Homologous Superfamily 3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family Glucose-1-phosphate thymidylyltransferase

Enzyme Information

2.7.7.24
Glucose-1-phosphate thymidylyltransferase.
based on mapping to UniProt P37744
dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose.

UniProtKB Entries (1)

P37744
RMLA1_ECOLI
Escherichia coli K-12
Glucose-1-phosphate thymidylyltransferase 1

PDB Structure

PDB 1H5S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Kinetic and crystallographic analyses support a sequential-ordered bi bi catalytic mechanism for Escherichia coli glucose-1-phosphate thymidylyltransferase.
Zuccotti, S., Zanardi, D., Rosano, C., Sturla, L., Tonetti, M., Bolognesi, M.
J. Mol. Biol.