CATH Domain 1h3mA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
	3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Enzyme Information

2.7.7.60

2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.

based on mapping to UniProt Q46893

CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.

-!- ATP or UTP can replace CTP, but both are less effective. -!- GTP and TTP are not substrates. -!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

Q46893

ISPD_ECOLI

Escherichia coli K-12

2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

PDB Structure

PDB	1H3M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of a Tetragonal Crystal Form of Escherichia Coli 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase Kemp, L.E., Bond, C.S., Hunter, W.N. Acta Crystallogr.,Sect.D