CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.1400 | Penicillin amidase (Acylase) alpha subunit, N-terminal domain |
|
1.10.1400.10 | Aminohydrolase, alpha-helical knob region |
Domain Context
CATH Clusters
| Superfamily | 1.10.1400.10 |
| Functional Family |
Enzyme Information
| 3.5.1.11 |
Penicillin amidase.
based on mapping to UniProt P06875
Penicillin + H(2)O = a carboxylate + 6-aminopenicillanate.
|
UniProtKB Entries (1)
| P06875 |
PAC_ECOLX
Escherichia coli
Penicillin G acylase
|
PDB Structure
| PDB | 1H2G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mutations of Penicillin Acylase Residue B71 Extend Substrate Specificity by Decreasing Steric Constraints for Substrate Binding
Biochem.J.
|
