CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.190 | Phosphatidylinositol (PI) phosphodiesterase |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol (PI) phosphodiesterase |
| Functional Family | 1-phosphatidylinositol phosphodiesterase |
Enzyme Information
| 4.6.1.13 |
Phosphatidylinositol diacylglycerol-lyase.
based on mapping to UniProt P14262
1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1,2-cyclic phosphate + 1,2-diacyl-sn-glycerol.
-!- This enzyme is bacterial. -!- Activity is also found in animals, but this activity is due to the presence of EC 3.1.4.11. -!- Formerly EC 3.1.4.10.
|
UniProtKB Entries (1)
| P14262 |
PLC_BACCE
Bacillus cereus
1-phosphatidylinositol phosphodiesterase
|
PDB Structure
| PDB | 1GYM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with glucosaminyl(alpha 1-->6)-D-myo-inositol, an essential fragment of GPI anchors.
Biochemistry
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