CATH Classification

Domain Context

CATH Clusters

Superfamily P1 Nuclease
Functional Family

Enzyme Information

3.1.4.3
Phospholipase C.
based on mapping to UniProt P0C216
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.

UniProtKB Entries (1)

P0C216
PHLC1_CLOPE
Clostridium perfringens str. 13
Phospholipase C

PDB Structure

PDB 1GYG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the C. Perfringens Alpha-Toxin with the Active Site Closed by a Flexible Loop Region
Eaton, J.T., Naylor, C., Howells, A., Moss, D., Titball, R.W., Basak, A.K.
J.Mol.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...