CATH Domain 1gvkB01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Chymotrypsin-like elastase family member 1

Enzyme Information

3.4.21.36

Pancreatic elastase.

based on mapping to UniProt P00772

Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.

-!- Formed by activation of proelastase from mammalian pancreas by trypsin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.7 and EC 3.4.21.11.

UniProtKB Entries (1)

P00772

CELA1_PIG

Sus scrofa

Chymotrypsin-like elastase family member 1

PDB Structure

PDB	1GVK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	X-Ray Structure of a Serine Protease Acyl-Enzyme Complex at 0.95-A Resolution. Katona, G., Wilmouth, R.C., Wright, P.A., Berglund, G.I., Hajdu, J., Neutze, R., Schofield, C.J. J.Biol.Chem.