CATH Domain 1gv0A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.110	L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
	3.90.110.10	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family	Malate dehydrogenase

Enzyme Information

1.1.1.37

Malate dehydrogenase.

based on mapping to UniProt P80039

(S)-malate + NAD(+) = oxaloacetate + NADH.

-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

MDH_CHLTE

Chlorobaculum tepidum TLS

Malate dehydrogenase

PDB Structure

PDB	1GV0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases Dalhus, B., Saarinen, M., Sauer, U.H., Eklund, P., Johansson, K., Karlsson, A., Ramaswamy, S., Bjork, A., Synstad, B., Naterstad, K., Sirevag, R., Eklund, H. J.Mol.Biol.