CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P00593
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P00593
PA21B_BOVIN
Bos taurus
Phospholipase A2

PDB Structure

PDB 1GH4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2.
Rajakannan, V., Yogavel, M., Poi, M.J., Jeyaprakash, A.A., Jeyakanthan, J., Velmurugan, D., Tsai, M.D., Sekar, K.
J.Mol.Biol.
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