CATH Domain 1g0dA04

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Protein-glutamine gamma-glutamyltransferase 2

Enzyme Information

2.3.2.13

Protein-glutamine gamma-glutamyltransferase.

based on mapping to UniProt P52181

A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)- (gamma-glutamyl)-L-lysine cross-link + NH(3).

-!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine cross-links.

UniProtKB Entries (1)

P52181

TGM2_PAGMA

Pagrus major

Protein-glutamine gamma-glutamyltransferase 2

PDB Structure

PDB	1G0D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of red sea bream transglutaminase. Noguchi, K., Ishikawa, K., Yokoyama, K.i., Ohtsuka, T., Nio, N., Suzuki, E. J.Biol.Chem.