CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1280 | Monooxygenase |
|
1.20.1280.30 | Methane monooxygenase, gamma chain, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Methane monooxygenase, gamma chain, domain 2 |
| Functional Family |
Enzyme Information
| 1.14.13.25 |
Methane monooxygenase (soluble).
based on mapping to UniProt P11987
Methane + NAD(P)H + O(2) = methanol + NAD(P)(+) + H(2)O.
-!- The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3. -!- Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO(2), ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.
|
UniProtKB Entries (1)
| P18798 |
MEMB_METCA
Methylococcus capsulatus str. Bath
Methane monooxygenase component A beta chain
|
PDB Structure
| PDB | 1FZ6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray crystal structure of alcohol products bound at the active site of soluble methane monooxygenase hydroxylase.
J.Am.Chem.Soc.
|
