CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonucleotide Reductase, subunit A
Functional Family

Enzyme Information

1.14.13.25
Methane monooxygenase (soluble).
based on mapping to UniProt P18798
Methane + NAD(P)H + O(2) = methanol + NAD(P)(+) + H(2)O.
-!- The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3. -!- Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO(2), ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.

UniProtKB Entries (1)

P18798
MEMB_METCA
Methylococcus capsulatus str. Bath
Methane monooxygenase component A beta chain

PDB Structure

PDB 1FYZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site.
Whittington, D.A., Lippard, S.J.
J.Am.Chem.Soc.