CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.1520 | PX Domain | |
3.30.1520.20 | Exonuclease ExoI, domain 2 |
Domain Context
CATH Clusters
Superfamily | Exonuclease ExoI, domain 2 |
Functional Family | Exodeoxyribonuclease I |
Enzyme Information
3.1.11.1 |
Exodeoxyribonuclease I.
based on mapping to UniProt P04995
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for single-stranded DNA. -!- The Escherichia coli enzyme hydrolyzes glucosylated DNA. -!- Similar enzymes; mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases. -!- Formerly EC 3.1.4.25.
|
UniProtKB Entries (1)
P04995 |
EX1_ECOLI
Escherichia coli K-12
Exodeoxyribonuclease I
|
PDB Structure
PDB | 1FXX |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structure of Escherichia coli exonuclease I suggests how processivity is achieved.
Nat.Struct.Biol.
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