CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.1230 | Nucleotide cyclase |
Domain Context
CATH Clusters
| Superfamily | Nucleotide cyclase |
| Functional Family | Receptor-type adenylate cyclase GRESAG 4, putative |
Enzyme Information
| 4.6.1.1 |
Adenylate cyclase.
based on mapping to UniProt Q99280
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.
|
UniProtKB Entries (1)
| Q99280 |
CY43_TRYBB
Trypanosoma brucei brucei
Receptor-type adenylate cyclase GRESAG 4.3
|
PDB Structure
| PDB | 1FX4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state.
EMBO J.
|
