CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.80 | Trefoil |
|
2.80.10 | Trefoil (Acidic Fibroblast Growth Factor, subunit A) |
|
2.80.10.50 |
Domain Context
CATH Clusters
| Superfamily | 2.80.10.50 |
| Functional Family | Tetanus toxin |
Enzyme Information
| 3.4.24.68 |
Tentoxilysin.
based on mapping to UniProt P04958
Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.
-!- Belongs to peptidase family M27.
|
UniProtKB Entries (1)
| P04958 |
TETX_CLOTE
Clostridium tetani E88
Tetanus toxin
|
PDB Structure
| PDB | 1FV3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.
J.Biol.Chem.
|
