CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Neutrophil elastase |
Enzyme Information
| 3.4.21.76 |
Myeloblastin.
based on mapping to UniProt P24158
Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.
-!- Not inhibited by secretory leukocyte proteinase inhibitor. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
| P24158 |
PRTN3_HUMAN
Homo sapiens
Myeloblastin
|
PDB Structure
| PDB | 1FUJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies.
J.Mol.Biol.
|
