CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family

Enzyme Information

3.4.11.10
Bacterial leucyl aminopeptidase.
based on mapping to UniProt Q01693
Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.
-!- Similar aminopeptidases were isolated from Escherichia coli and Staphylococcus thermophilus. -!- Belongs to peptidase families M17 and M28.

UniProtKB Entries (1)

Q01693
AMPX_VIBPR
Vibrio proteolyticus
Bacterial leucyl aminopeptidase

PDB Structure

PDB 1FT7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis.
Stamper, C., Bennett, B., Edwards, T., Holz, R.C., Ringe, D., Petsko, G.
Biochemistry