CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | T cell lymphoma invasion and metastasis 1 |
Enzyme Information
UniProtKB Entries (2)
| Q60610 |
TIAM1_MOUSE
Mus musculus
T-lymphoma invasion and metastasis-inducing protein 1
|
| P63000 |
RAC1_HUMAN
Homo sapiens
Ras-related C3 botulinum toxin substrate 1
|
PDB Structure
| PDB | 1FOE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Nature
|
