CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.20 | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 |
|
3.60.20.10 | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 |
| Functional Family |
Enzyme Information
| 3.5.1.93 |
Glutaryl-7-aminocephalosporanic-acid acylase.
based on mapping to UniProt Q9L5D6
(7R)-7-(4-carboxybutanamido)cephalosporanate + H(2)O = (7R)-7- aminocephalosporanate + glutarate.
-!- Forms 7-aminocephalosporanic acid, a key intermediate in the synthesis of cephem antibiotics. -!- It reacts only weakly with cephalosporin C.
|
UniProtKB Entries (1)
| Q9L5D6 |
G7AC_BREDI
Brevundimonas diminuta
Glutaryl-7-aminocephalosporanic-acid acylase
|
PDB Structure
| PDB | 1FM2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The 2.0 A crystal structure of cephalosporin acylase.
Structure Fold.Des.
|
