CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.20 | Alpha-Beta Barrel | |
3.20.20 | TIM Barrel | |
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
Superfamily | Aldolase class I |
Functional Family | N-acetylneuraminate lyase |
Enzyme Information
4.1.3.3 |
N-acetylneuraminate lyase.
based on mapping to UniProt P44539
N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.
-!- Also acts on N-glycoloylneuraminate, and on O-acetylated sialic acids, other than 4-O-acetylated derivatives.
|
UniProtKB Entries (1)
P44539 |
NANA_HAEIN
Haemophilus influenzae Rd KW20
N-acetylneuraminate lyase
|
PDB Structure
PDB | 1F6P |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol.
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