CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q92830
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-
Transferring groups other than amino-acyl groups.
based on mapping to UniProt Q92830

UniProtKB Entries (1)

Q92830
KAT2A_HUMAN
Homo sapiens
Histone acetyltransferase KAT2A

PDB Structure

PDB 1F68
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.
Hudson, B.P., Martinez-Yamout, M.A., Dyson, H.J., Wright, P.E.
J.Mol.Biol.