CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Lactonizing lipase

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt P26876
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (1)

P26876
LIP_PSEAE
Pseudomonas aeruginosa PAO1
Triacylglycerol lipase

PDB Structure

PDB 1EX9
External Links
Method X-RAY DIFFRACTION
Organism Pseudomonas
Primary Citation
Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases.
Nardini, M., Lang, D.A., Liebeton, K., Jaeger, K.E., Dijkstra, B.W.
J.Biol.Chem.