CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.70 | Cathepsin B; Chain A | |
3.90.70.10 | Cysteine proteinases |
Domain Context
CATH Clusters
Superfamily | Cysteine proteinases |
Functional Family | Cruzipain |
Enzyme Information
3.4.22.51 |
Cruzipain.
based on mapping to UniProt P25779
Broad endopeptidase specificity similar to that of cathepsin L.
-!- Is located in the digestive vacuoles of the parasitic trypanosome and contributes to the nutrition of the organism by digestion of host proteins. -!- Belongs to peptidase family C1.
|
UniProtKB Entries (1)
P25779 |
CYSP_TRYCR
Trypanosoma cruzi
Cruzipain
|
PDB Structure
PDB | 1EWO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal Structure of Cruzain bound to WRR-204
To be Published
|