CATH Classification

Domain Context

CATH Clusters

Superfamily Aromatic compound dioxygenase
Functional Family

Enzyme Information

1.13.11.3
Protocatechuate 3,4-dioxygenase.
based on mapping to UniProt P20372
3,4-dihydroxybenzoate + O(2) = 3-carboxy-cis,cis-muconate.
-!- The enzyme, which participates in the degradation of aromatic compounds, catalyzes the intradiol addition of both oxygen atoms from molecular oxygen, resulting in ortho-cleavage of the aromatic ring. -!- The type of cleavage leads to mineralization via the intermediate 3-oxoadipate. -!- Formerly EC 1.13.1.3 and EC 1.99.2.3.

UniProtKB Entries (1)

P20371
PCXA_ACIAD
Acinetobacter baylyi ADP1
Protocatechuate 3,4-dioxygenase alpha chain

PDB Structure

PDB 1EOB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Acinetobacter strain ADP1 protocatechuate 3, 4-dioxygenase at 2.2 A resolution: implications for the mechanism of an intradiol dioxygenase.
Vetting, M.W., D'Argenio, D.A., Ornston, L.N., Ohlendorf, D.H.
Biochemistry