CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P61889
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P61889
MDH_ECOLI
Escherichia coli K-12
Malate dehydrogenase

PDB Structure

PDB 1EMD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a ternary complex of Escherichia coli malate dehydrogenase citrate and NAD at 1.9 A resolution.
Hall, M.D., Banaszak, L.J.
J.Mol.Biol.
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