CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Ribosomal RNA large subunit methyltransferase E |
Enzyme Information
| 2.1.1.166 |
23S rRNA (uridine(2552)-2'-O)-methyltransferase.
based on mapping to UniProt P0C0R7
S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = S-adenosyl-L- homocysteine + 2'-O-methyluridine(2552) in 23S rRNA.
-!- The enzyme catalyzes the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA.
|
UniProtKB Entries (1)
| P0C0R7 |
RLME_ECOLI
Escherichia coli K-12
Ribosomal RNA large subunit methyltransferase E
|
PDB Structure
| PDB | 1EJ0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
RNA methylation under heat shock control.
Mol.Cell
|