CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.640 | Myeloperoxidase, subunit C | |
1.10.640.10 | Haem peroxidase domain superfamily, animal type |
Domain Context
CATH Clusters
Superfamily | Haem peroxidase domain superfamily, animal type |
Functional Family | Prostaglandin G/H synthase 2 |
Enzyme Information
1.14.99.1 |
Prostaglandin-endoperoxide synthase.
based on mapping to UniProt P05979
Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.
-!- Acts both as a dioxygenase and as a peroxidase.
|
UniProtKB Entries (1)
P05979 |
PGH1_SHEEP
Ovis aries
Prostaglandin G/H synthase 1
|
PDB Structure
PDB | 1EBV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional characterization of enzyme-inhibitor interactions.
Mol.Pharmacol.
|