CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1370 | Aspartate/ornithine carbamoyltransferase |
Domain Context
CATH Clusters
Superfamily | Aspartate/ornithine carbamoyltransferase |
Functional Family | Ornithine carbamoyltransferase |
Enzyme Information
2.1.3.3 |
Ornithine carbamoyltransferase.
based on mapping to UniProt P04391
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
-!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.
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UniProtKB Entries (1)
P04391 |
OTC1_ECOLI
Escherichia coli K-12
Ornithine carbamoyltransferase subunit I
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PDB Structure
PDB | 1DUV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Mechanism of inactivation of ornithine transcarbamoylase by Ndelta -(N'-Sulfodiaminophosphinyl)-L-ornithine, a true transition state analogue? Crystal structure and implications for catalytic mechanism.
J.Biol.Chem.
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