CATH Classification

Domain Context

CATH Clusters

Superfamily Lyase 2-enoyl-coa Hydratase, Chain A, domain 2
Functional Family Probable enoyl-CoA hydratase, mitochondrial

Enzyme Information

4.2.1.17
Enoyl-CoA hydratase.
based on mapping to UniProt P14604
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
-!- Acts in the reverse direction. -!- With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).

UniProtKB Entries (1)

P14604
ECHM_RAT
Rattus norvegicus
Enoyl-CoA hydratase, mitochondrial

PDB Structure

PDB 1DUB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket.
Engel, C.K., Mathieu, M., Zeelen, J.P., Hiltunen, J.K., Wierenga, R.K.
EMBO J.