CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.12 | Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 | |
1.10.12.10 | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
Domain Context
CATH Clusters
Superfamily | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
Functional Family | Probable enoyl-CoA hydratase, mitochondrial |
Enzyme Information
4.2.1.17 |
Enoyl-CoA hydratase.
based on mapping to UniProt P14604
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
-!- Acts in the reverse direction. -!- With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).
|
UniProtKB Entries (1)
P14604 |
ECHM_RAT
Rattus norvegicus
Enoyl-CoA hydratase, mitochondrial
|
PDB Structure
PDB | 1DUB |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket.
EMBO J.
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