CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family |
Enzyme Information
1.1.1.363 |
Glucose-6-phosphate dehydrogenase (NAD(P)(+)).
based on mapping to UniProt P11411
D-glucose 6-phosphate + NAD(P)(+) = 6-phospho-D-glucono-1,5-lactone + NAD(P)H.
-!- The enzyme catalyzes a step of the pentose phosphate pathway. -!- The enzyme from the Gram-positive bacterium Leuconostoc mesenteroides prefers NADP(+) while the enzyme from the Gram-negative bacterium Gluconacetobacter xylinus prefers NAD(+). -!- Cf. EC 1.1.1.49 and EC 1.1.1.388.
|
UniProtKB Entries (1)
P11411 |
G6PD_LEUME
Leuconostoc mesenteroides
Glucose-6-phosphate 1-dehydrogenase
|
PDB Structure
PDB | 1DPG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
The three-dimensional structure of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 A resolution.
Structure
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