CATH Classification

Domain Context

CATH Clusters

Superfamily Flavocytochrome C3; Chain A
Functional Family Fumarate reductase flavoprotein subunit

Enzyme Information

1.3.5.4
Fumarate reductase (quinol).
based on mapping to UniProt P83223
Succinate + a quinone = fumarate + a quinol.
-!- The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain. -!- The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, to which it is closely related.

UniProtKB Entries (1)

P83223
FRDA_SHEON
Shewanella oneidensis MR-1
Fumarate reductase flavoprotein subunit

PDB Structure

PDB 1D4D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1.
Leys, D., Tsapin, A.S., Nealson, K.H., Meyer, T.E., Cusanovich, M.A., Van Beeumen, J.J.
Nat.Struct.Biol.