CATH Domain 1d4cA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.700	Flavocytochrome C3; Chain A, domain 1
	3.90.700.10	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain

Domain Context

CATH Clusters

Superfamily	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
Functional Family	NADH-dependent fumarate reductase

Enzyme Information

1.3.5.4

Fumarate reductase (quinol).

based on mapping to UniProt P83223

Succinate + a quinone = fumarate + a quinol.

-!- The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain. -!- The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, to which it is closely related.

UniProtKB Entries (1)

P83223

FRDA_SHEON

Shewanella oneidensis MR-1

Fumarate reductase flavoprotein subunit

PDB Structure

PDB	1D4C
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1. Leys, D., Tsapin, A.S., Nealson, K.H., Meyer, T.E., Cusanovich, M.A., Van Beeumen, J.J. Nat.Struct.Biol.