CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family 3-isopropylmalate dehydrogenase

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt P37412
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

P37412
LEU3_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
3-isopropylmalate dehydrogenase

PDB Structure

PDB 1CNZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structures of Eschericia Coli and Salmonella Typhimurium 3- Isopropylmalate Dehydrogenase and Comparison with Their Thermophilic Counterpart from Thermus Thermophilus
Wallon, G., Kryger, G., Lovett, S.T., Oshima, T., Ringe, D., Petsko, G.A.
J.Mol.Biol.
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