CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.718 | Isopropylmalate Dehydrogenase |
|
3.40.718.10 | Isopropylmalate Dehydrogenase |
Domain Context
CATH Clusters
| Superfamily | Isopropylmalate Dehydrogenase |
| Functional Family | 3-isopropylmalate dehydrogenase |
Enzyme Information
| 1.1.1.85 |
3-isopropylmalate dehydrogenase.
based on mapping to UniProt P30125
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.
|
UniProtKB Entries (1)
| P30125 |
LEU3_ECOLI
Escherichia coli K-12
3-isopropylmalate dehydrogenase
|
PDB Structure
| PDB | 1CM7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus.
J.Mol.Biol.
|
