CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family |
Enzyme Information
| 1.1.1.80 |
Isopropanol dehydrogenase (NADP(+)).
based on mapping to UniProt P14941
Propan-2-ol + NADP(+) = acetone + NADPH.
-!- Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.
|
UniProtKB Entries (1)
| P14941 |
ADH_THEBR
Thermoanaerobacter brockii
NADP-dependent isopropanol dehydrogenase
|
PDB Structure
| PDB | 1BXZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of a thermophilic alcohol dehydrogenase substrate complex suggests determinants of substrate specificity and thermostability.
Proteins
|
