CATH Domain 1bgxT02
|1.10.150||DNA polymerase; domain 1|
|126.96.36.199||5' to 3' exonuclease, C-terminal subdomain|
|Superfamily||5' to 3' exonuclease, C-terminal subdomain|
|Functional Family||DNA polymerase I|
DNA-directed DNA polymerase.
based on mapping to UniProt P19821
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 188.8.131.52.
UniProtKB Entries (1)
DNA polymerase I, thermostable
Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.