CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.950.10
Functional Family dITP/XTP pyrophosphatase

Enzyme Information

3.6.1.66
XTP/dITP diphosphatase.
based on mapping to UniProt Q57679
(1) XTP + H(2)O = XMP + diphosphate. (2) dITP + H(2)O = dIMP + diphosphate. (3) ITP + H(2)O = IMP + diphosphate.
-!- The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP, dITP and ITP.

UniProtKB Entries (1)

Q57679
IXTPA_METJA
Methanocaldococcus jannaschii DSM 2661
DITP/XTP pyrophosphatase

PDB Structure

PDB 1B78
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based identification of a novel NTPase from Methanococcus jannaschii.
Hwang, K.Y., Chung, J.H., Kim, S.H., Han, Y.S., Cho, Y.
Nat.Struct.Biol.
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