CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.2000 | Glycogen Phosphorylase B; |
Domain Context
CATH Clusters
Superfamily | Glycogen Phosphorylase B; |
Functional Family | Glycogen phosphorylase, muscle form |
Enzyme Information
2.4.1.1 |
Glycogen phosphorylase.
based on mapping to UniProt P00489
((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.
-!- This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans. -!- Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers. -!- The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin. -!- The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc.
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UniProtKB Entries (1)
P00489 |
PYGM_RABIT
Oryctolagus cuniculus
Glycogen phosphorylase, muscle form
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PDB Structure
PDB | 1B4D |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure.
Protein Sci.
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