CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.20 | 5' to 3' exonuclease, C-terminal subdomain |
Domain Context
CATH Clusters
| Superfamily | 5' to 3' exonuclease, C-terminal subdomain |
| Functional Family | Flap endonuclease 1 |
Enzyme Information
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt O93634
|
UniProtKB Entries (1)
| O93634 |
FEN_PYRFU
Pyrococcus furiosus DSM 3638
Flap endonuclease 1
|
PDB Structure
| PDB | 1B43 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity.
Cell(Cambridge,Mass.)
|
