CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.600 | ECO RV Endonuclease; Chain A | |
3.40.600.10 | DNA mismatch repair MutH/Restriction endonuclease, type II |
Domain Context
CATH Clusters
Superfamily | DNA mismatch repair MutH/Restriction endonuclease, type II |
Functional Family |
Enzyme Information
3.1.21.4 |
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P04390
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
P04390 |
T2E5_ECOLX
Escherichia coli
Type-2 restriction enzyme EcoRV
|
PDB Structure
PDB | 1AZ0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol.
|