CATH Classification

Domain Context

CATH Clusters

Superfamily Metallocarboxypeptidase-like
Functional Family Carboxypeptidase A5

Enzyme Information

3.4.17.15
Carboxypeptidase A2.
based on mapping to UniProt P48052
Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a preference for bulkier C-terminal residues.
-!- Isolated from rat pancreas but not present in cattle pancreas. -!- Belongs to peptidase family M14.

UniProtKB Entries (1)

P48052
CBPA2_HUMAN
Homo sapiens
Carboxypeptidase A2

PDB Structure

PDB 1AYE
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.
Garcia-Saez, I., Reverter, D., Vendrell, J., Aviles, F.X., Coll, M.
EMBO J.