CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.30 | Roll | |
2.30.30 | SH3 type barrels. | |
2.30.30.40 | SH3 Domains |
Domain Context
CATH Clusters
Superfamily | SH3 Domains |
Functional Family | Tyrosine-protein kinase |
Enzyme Information
2.7.10.2 |
Non-specific protein-tyrosine kinase.
based on mapping to UniProt Q03526
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
Q03526 |
ITK_MOUSE
Mus musculus
Tyrosine-protein kinase ITK/TSK
|
PDB Structure
PDB | 1AWJ |
External Links | |
Method | SOLUTION NMR |
Organism | Escherichia |
Primary Citation |
Regulatory intramolecular association in a tyrosine kinase of the Tec family.
Nature
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