CATH Domain 1aw0A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.100

Domain Context

CATH Clusters

Superfamily	3.30.70.100
Functional Family	ATPase copper transporting beta

Enzyme Information

7.2.2.8

P-type Cu(+) transporter.

based on mapping to UniProt Q04656

ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).

-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.

UniProtKB Entries (1)

Q04656

ATP7A_HUMAN

Homo sapiens

Copper-transporting ATPase 1

PDB Structure

PDB	1AW0
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase. Gitschier, J., Moffat, B., Reilly, D., Wood, W.I., Fairbrother, W.J. Nat.Struct.Biol.